📘 Study MCQs
Q1. The rhythmic contraction and relaxation of the heart is called:
A. Pulse
B. Heartbeat
C. Blood pressure
D. Circulation
B. HeartbeatThe heartbeat is the complete sequence of contraction (systole) and relaxation (diastole) of the heart chambers. Each heartbeat pumps blood into the arteries. An adult human heart beats about 60 to 100 times per minute at rest. The heartbeat is controlled by the sinoatrial node, often called the natural pacemaker.
Q2. The wave of pressure that travels through the arteries when the heart beats is called:
A. Heartbeat
B. Pulse
C. Blood pressure
D. Cardiac output
B. PulsePulse is the rhythmic expansion and contraction of arterial walls caused by the pressure wave generated when the left ventricle pumps blood into the aorta. The pulse can be felt at various points on the body, such as the wrist (radial artery) or neck (carotid artery). The pulse rate equals the heart rate.
Q3. The force exerted by blood against the walls of blood vessels is called:
A. Pulse
B. Heart rate
C. Blood pressure
D. Osmotic pressure
C. Blood pressureBlood pressure is the pressure exerted by circulating blood on the walls of arteries, veins, and capillaries. It is highest in arteries and lowest in veins. Blood pressure is measured in millimeters of mercury (mm Hg) and is recorded as two numbers: systolic pressure (during heart contraction) over diastolic pressure (during heart relaxation).
Q4. The higher number in a blood pressure reading (e.g., 120 in 120/80) represents:
A. Diastolic pressure
B. Pulse pressure
C. Systolic pressure
D. Mean arterial pressure
C. Systolic pressureSystolic pressure is the pressure in the arteries when the ventricles contract and pump blood out of the heart. It is the higher number in a blood pressure reading. Normal systolic pressure for a healthy adult is around 120 mm Hg. It reflects the force of blood against artery walls during heartbeats.
Q5. The lower number in a blood pressure reading (e.g., 80 in 120/80) represents:
A. Systolic pressure
B. Diastolic pressure
C. Pulse rate
D. Stroke volume
B. Diastolic pressureDiastolic pressure is the pressure in the arteries when the ventricles relax and the heart fills with blood. It is the lower number in a blood pressure reading. Normal diastolic pressure for a healthy adult is around 80 mm Hg. It represents the constant pressure in arteries between heartbeats.
Q6. The normal blood pressure for a healthy adult human is approximately:
A. 90/60 mm Hg
B. 120/80 mm Hg
C. 150/100 mm Hg
D. 180/120 mm Hg
B. 120/80 mm HgThe ideal normal blood pressure for an adult is about 120 mm Hg systolic and 80 mm Hg diastolic, written as 120/80 mm Hg. Readings below 90/60 mm Hg are considered low blood pressure (hypotension), while readings consistently above 130/80 mm Hg may indicate high blood pressure (hypertension).
Q7. The process of removing metabolic waste products from the body is called:
A. Digestion
B. Circulation
C. Excretion
D. Respiration
C. ExcretionExcretion is the biological process by which organisms remove harmful metabolic wastes from their bodies. These wastes include carbon dioxide, urea, uric acid, ammonia, excess water, and salts. Excretion is essential because accumulation of wastes can damage cells and lead to death. Different organs are involved in excretion.
Q8. Which of the following is not an excretory product in humans?
A. Carbon dioxide
B. Urea
C. Oxygen
D. Excess water
C. OxygenOxygen is not a waste product; it is essential for cellular respiration. The main excretory products in humans are carbon dioxide (from lungs), urea (from kidneys), excess water and salts (from kidneys and skin), and bile pigments (from liver). Oxygen is taken in, not removed as waste.
Q9. In small aquatic animals like Amoeba and Paramecium, excretion occurs mainly by:
A. Kidneys
B. Diffusion through the body surface
C. Lungs
D. Specialized excretory organs called nephridia
B. Diffusion through the body surfaceSmall aquatic animals have a large surface area to volume ratio. Their body surface is thin and in direct contact with surrounding water. Ammonia (their main waste) and carbon dioxide diffuse directly out through the cell membrane or body surface into the water. They do not need complex excretory organs.
Q10. The process by which excess water is removed from a unicellular freshwater organism like Amoeba is called:
A. Diffusion
B. Osmosis
C. Transpiration
D. Active transport using contractile vacuole
D. Active transport using contractile vacuoleFreshwater unicellular organisms like Amoeba constantly take in water by osmosis because their cytoplasm is more concentrated than the surrounding water. The contractile vacuole collects this excess water and actively pumps it out of the cell. This prevents the cell from bursting. It is a form of excretion.
Q11. Which organ in humans is primarily responsible for excreting carbon dioxide?
A. Kidneys
B. Skin
C. Lungs
D. Liver
C. LungsThe lungs excrete carbon dioxide, which is a waste product of cellular respiration. When we exhale, carbon dioxide diffuses from the blood into the alveoli of the lungs and is then expelled. The lungs also excrete small amounts of water vapor. Without this excretion, blood pH would become dangerously acidic.
Q12. The skin helps in excretion by removing:
A. Urea and carbon dioxide
B. Water, salts, and small amounts of urea (as sweat)
C. Only carbon dioxide
D. Bile pigments
B. Water, salts, and small amounts of urea (as sweat)Sweat glands in the skin produce sweat, which contains water, sodium chloride (salt), and small amounts of urea and lactic acid. When sweat evaporates, it cools the body, but the process also removes these wastes. On a hot day, the skin can excrete several liters of water and significant amounts of salt.
Q13. The large intestine (colon) is involved in excretion by:
A. Filtering blood
B. Removing carbon dioxide
C. Eliminating undigested food and some waste products like bile pigments
D. Producing urea
C. Eliminating undigested food and some waste products like bile pigmentsThe large intestine forms and stores feces, which consists mainly of undigested food, bacteria, water, and some excretory products. Bile pigments (from breakdown of hemoglobin) are excreted in feces, giving it its brown color. However, the large intestine is primarily for defecation, not for metabolic waste excretion.
Q14. The liver is an excretory organ because it:
A. Produces urine
B. Filters blood
C. Converts ammonia into urea and excretes bile pigments
D. Removes carbon dioxide
C. Converts ammonia into urea and excretes bile pigmentsThe liver performs several excretory functions. It converts toxic ammonia (from protein breakdown) into less toxic urea, which is then sent to the kidneys. The liver also produces bile, which contains bilirubin (a waste product from old red blood cells). Bile pigments are excreted into the small intestine and leave the body in feces.
Q15. The main nitrogenous waste product in humans is:
A. Ammonia
B. Uric acid
C. Urea
D. Creatinine
C. UreaHumans are ureotelic animals, meaning they excrete urea as their main nitrogenous waste. Urea is produced in the liver from ammonia (which is highly toxic) through the urea cycle. Urea is less toxic and requires less water for excretion than ammonia. About 25-30 grams of urea are excreted daily in urine.
Q16. The functional unit of the human kidney is the:
A. Neuron
B. Nephron
C. Ureter
D. Alveolus
B. NephronThe nephron is the microscopic structural and functional unit of the kidney. Each human kidney contains about 1 to 1.5 million nephrons. Each nephron consists of a glomerulus (filtering unit) and a renal tubule (where reabsorption and secretion occur). Nephrons filter blood and produce urine.
Q17. The tube that carries urine from each kidney to the urinary bladder is called:
A. Urethra
B. Ureter
C. Nephron
D. Collecting duct
B. UreterEach kidney has a ureter, a muscular tube about 25-30 cm long in humans. Urine produced in the kidneys drains into the renal pelvis and then moves down the ureters to the urinary bladder by peristaltic contractions. The ureters have valves at their entrance to the bladder to prevent backflow of urine.
Q18. The muscular sac that stores urine until it is expelled from the body is the:
A. Kidney
B. Ureter
C. Urinary bladder
D. Urethra
C. Urinary bladderThe urinary bladder is a hollow, muscular, and elastic organ located in the pelvis. It stores urine produced by the kidneys. In an adult, the bladder can hold approximately 400-600 mL of urine comfortably, though it can stretch to hold more. When it becomes full, nerve signals trigger the urge to urinate.
Q19. The tube that carries urine from the urinary bladder to the outside of the body is the:
A. Ureter
B. Nephron
C. Urethra
D. Collecting duct
C. UrethraThe urethra is a thin tube that connects the urinary bladder to the external opening. In males, the urethra is longer (about 20 cm) and also carries semen; in females, it is shorter (about 4 cm) and only carries urine. Sphincter muscles control the release of urine through the urethra.
Q20. The average amount of urine passed by a healthy adult human in 24 hours is approximately:
A. 500 mL
B. 1 to 1.8 liters
C. 3 to 4 liters
D. 5 to 6 liters
B. 1 to 1.8 litersA healthy adult produces about 1 to 1.8 liters of urine per day, depending on fluid intake, diet, temperature, and physical activity. The minimum amount needed to excrete waste products is about 500 mL per day. Urine output less than 400 mL per day is called oliguria, and less than 50 mL is called anuria, both indicating kidney problems.
Q21. The process that artificially removes waste products from the blood when kidneys fail is called:
A. Dialysis
B. Transfusion
C. Transplantation
D. Filtration
A. DialysisDialysis is a medical procedure that performs the function of healthy kidneys when they fail. It removes excess water, urea, creatinine, and other toxins from the blood using a machine and a semipermeable membrane. The two main types are hemodialysis (blood is filtered outside the body) and peritoneal dialysis (using the abdominal lining).
Q22. In hemodialysis, the patient’s blood is passed through a machine containing a:
A. Filter paper
B. Dialyzer (artificial kidney) with a semipermeable membrane
C. Centrifuge
D. Chemical reactor
B. Dialyzer (artificial kidney) with a semipermeable membraneThe dialyzer, also called an artificial kidney, contains thousands of hollow fibers with semipermeable membranes. Blood flows through these fibers while a dialysis fluid (dialysate) flows on the outside. Wastes diffuse from the blood into the dialysate, while useful substances like glucose and electrolytes are kept in the blood.
Q23. Which part of the nephron is responsible for the actual filtration of blood?
A. Loop of Henle
B. Collecting duct
C. Glomerulus
D. Distal convoluted tubule
C. GlomerulusThe glomerulus is a tiny ball of capillaries inside Bowman’s capsule. Blood pressure forces water, urea, glucose, salts, and other small molecules from the blood into Bowman’s capsule. This process is called ultrafiltration. Blood cells and large proteins remain in the blood because they are too large to pass through the filtration slits.
Q24. In the nephron, the reabsorption of glucose and most water back into the blood occurs in the:
A. Glomerulus
B. Renal tubule (proximal convoluted tubule)
C. Ureter
D. Urinary bladder
B. Renal tubule (proximal convoluted tubule)After filtration, the filtrate passes through the renal tubule. In the proximal convoluted tubule, about 65% of water, all glucose, amino acids, and many ions are reabsorbed back into the blood. Glucose is completely reabsorbed in healthy individuals; its presence in urine indicates diabetes. Reabsorption is an active process requiring energy.
Q25. The main nitrogenous waste excreted in human urine is:
A. Ammonia
B. Uric acid
C. Urea
D. Creatinine
C. UreaUrea is the primary nitrogenous waste in human urine, making up about 50% of the total dissolved solids. It is produced in the liver from ammonia and carbon dioxide. Normal urine contains about 20-35 grams of urea per day. Uric acid (from nucleic acid breakdown) and creatinine (from muscle metabolism) are present in smaller amounts.
Q26. The color of normal human urine is yellow due to the presence of:
A. Urea
B. Bilirubin
C. Urochrome (a bile pigment derivative)
D. Hemoglobin
C. Urochrome (a bile pigment derivative)Urochrome is a yellow pigment produced from the breakdown of hemoglobin (via bilirubin). It gives urine its characteristic pale yellow to amber color. The color can change with hydration: dark yellow urine indicates concentrated urine (less water), while nearly colorless urine indicates overhydration. Certain foods and drugs can also change urine color.
Q27. Which of the following animals excretes ammonia directly into water?
A. Human
B. Bird
C. Fish
D. Lizard
C. FishFish are ammonotelic, meaning they excrete ammonia directly. Ammonia is highly toxic but very soluble in water. Fish excrete ammonia through their gills directly into the surrounding water, where it dilutes rapidly. This requires large amounts of water, which is not a problem for aquatic animals. Humans convert ammonia to urea to save water.
Q28. Which of the following animals excretes uric acid to conserve water?
A. Human
B. Fish
C. Bird (e.g., pigeon)
D. Frog
C. Bird (e.g., pigeon)Birds and reptiles are uricotelic, excreting uric acid as a white paste. Uric acid is not very toxic and requires very little water to be removed. This is an adaptation for animals with eggs (uric acid does not harm the developing embryo) and for those living in dry environments. Birds do not have a urinary bladder to store liquid urine.
Q29. The presence of glucose in urine indicates a possible condition called:
A. Kidney stones
B. Diabetes mellitus
C. Uremia
D. Hypertension
B. Diabetes mellitusIn diabetes mellitus, blood glucose levels become very high (hyperglycemia). The nephrons cannot reabsorb all the glucose from the filtrate because the transport proteins are saturated. Excess glucose then appears in the urine (glucosuria). This is a common diagnostic sign of diabetes. Normally, urine contains no detectable glucose.
Q30. The term for the presence of excess urea and other waste products in the blood is:
A. Uremia
B. Hematuria
C. Proteinuria
D. Pyuria
A. UremiaUremia (or uremic syndrome) occurs when the kidneys fail to filter waste products properly. Urea, creatinine, and other toxins accumulate in the blood. Symptoms include fatigue, nausea, loss of appetite, confusion, and eventually coma. Dialysis or kidney transplant is required to treat severe uremia.
Q31. The part of the brain that controls the rate of heartbeat is the:
A. Cerebrum
B. Cerebellum
C. Medulla oblongata
D. Hypothalamus
C. Medulla oblongataThe medulla oblongata, located in the brainstem, contains the cardiac center that regulates heart rate. It receives signals from sensors (baroreceptors and chemoreceptors) and sends instructions through the autonomic nervous system to speed up or slow down the heart. This control is involuntary, meaning we do not consciously control our heart rate.
Q32. During exercise, the pulse rate increases because:
A. The heart needs to pump less blood
B. Muscles require more oxygen and produce more carbon dioxide
C. Blood pressure decreases
D. The body is trying to conserve energy
B. Muscles require more oxygen and produce more carbon dioxideDuring exercise, active muscles use more oxygen for cellular respiration and produce more carbon dioxide. The medulla oblongata detects increased carbon dioxide and decreased oxygen in blood and sends signals to increase heart rate and breathing rate. This delivers more oxygen to muscles and removes wastes faster.
Q33. Which of the following correctly lists the order of structures through which urine passes after leaving the kidney?
A. Ureter → urinary bladder → urethra
B. Urethra → ureter → urinary bladder
C. Urinary bladder → ureter → urethra
D. Ureter → urethra → urinary bladder
A. Ureter → urinary bladder → urethraUrine formed in the kidneys collects in the renal pelvis. It then flows down each ureter to the urinary bladder for storage. When the bladder contracts during urination, urine passes through the urethra to the outside of the body. The urethra is the final tube. Valves prevent backflow from bladder to ureters.
Q34. The process by which the kidneys regulate the water and salt balance in the blood is called:
A. Excretion
B. Osmoregulation
C. Filtration
D. Secretion
B. OsmoregulationOsmoregulation is the active regulation of the osmotic pressure of body fluids to maintain water and salt balance. The kidneys adjust the concentration of urine: when you are dehydrated, they produce concentrated (dark) urine; when you have drunk excess water, they produce dilute (pale) urine. This maintains a constant internal environment (homeostasis).
Q35. The instrument used to measure blood pressure is called:
A. Stethoscope
B. Thermometer
C. Sphygmomanometer
D. Pulse oximeter
C. SphygmomanometerA sphygmomanometer consists of an inflatable cuff, a pressure gauge (mercury or aneroid), and a stethoscope or electronic sensor. The cuff is placed around the upper arm and inflated to temporarily stop blood flow. As the cuff is deflated, the clinician listens for Korotkoff sounds to determine systolic and diastolic pressures.
Q36. The maximum amount of urine that an adult human bladder can hold is approximately:
A. 100 mL
B. 500 mL
C. 1 liter
D. 2 liters
1 liter (approx. 800-1000 mL)While the average urge to urinate occurs when the bladder contains about 300-400 mL, the bladder can stretch considerably. The maximum capacity of a healthy adult bladder is about 800 to 1000 mL (1 liter). Stretching beyond this can cause discomfort and potential damage. Frequent overstretching can weaken bladder muscles.
Q37. In a dialysis machine, the dialysis fluid (dialysate) contains:
A. Pure water only
B. Glucose, salts, and other substances at concentrations similar to normal blood but no urea
C. High concentration of urea
D. Blood cells
B. Glucose, salts, and other substances at concentrations similar to normal blood but no ureaThe dialysate has a composition similar to normal blood plasma except it contains no urea or other waste products. This creates a concentration gradient. Wastes (urea, creatinine) diffuse from the blood into the dialysate. At the same time, glucose and essential electrolytes are kept in the blood or added if needed. The dialysate is continuously refreshed.
Q38. Which of the following is not a function of the kidneys?
A. Removal of urea from blood
B. Regulation of blood pressure
C. Production of red blood cells (through erythropoietin)
D. Digestion of proteins
D. Digestion of proteinsProtein digestion occurs in the stomach and small intestine, not in the kidneys. The kidneys have many functions: excreting urea and toxins, regulating water and salt balance, maintaining blood pH, producing the hormone erythropoietin (stimulates RBC production), and activating vitamin D. They also help regulate blood pressure through the renin-angiotensin system.
Q39. The pulse can be felt most easily at which of the following arteries?
A. Radial artery (wrist)
B. Femoral artery (thigh)
C. Carotid artery (neck)
D. All of the above
D. All of the abovePulse can be felt at any superficial artery that lies over a bone. Common sites include the radial artery (wrist, most common), carotid artery (neck, used in emergencies), brachial artery (inside elbow), femoral artery (groin), and dorsalis pedis (foot). Each site is useful in different clinical situations.
Q40. The condition of persistently high blood pressure (above 130/80 mm Hg) is called:
A. Hypotension
B. Hypertension
C. Bradycardia
D. Tachycardia
B. HypertensionHypertension is a chronic medical condition where blood pressure is consistently elevated. It is often called the “silent killer” because it has no symptoms but can lead to heart attack, stroke, kidney failure, and other complications. Lifestyle changes (diet, exercise, reduced salt) and medications can control it. Normal is 120/80; 130/80 or higher is considered hypertension.
Q41. The condition of low blood pressure (below 90/60 mm Hg) is called:
A. Hypertension
B. Hypotension
C. Arrhythmia
D. Ischemia
B. HypotensionHypotension is abnormally low blood pressure. It may cause dizziness, fainting, blurred vision, and fatigue. Causes include dehydration, blood loss, certain medications, or heart problems. Some athletes naturally have low blood pressure without symptoms. Severe hypotension can be life-threatening because organs may not receive enough oxygen.
Q42. In the kidney, the blood vessel that carries filtered blood away from the glomerulus is the:
A. Afferent arteriole
B. Efferent arteriole
C. Renal vein
D. Peritubular capillary
B. Efferent arterioleBlood enters the glomerulus through the afferent arteriole (wider) and leaves through the efferent arteriole (narrower). The narrower efferent arteriole creates high pressure inside the glomerulus, which forces filtration. After leaving the glomerulus, the efferent arteriole branches into peritubular capillaries that surround the renal tubule for reabsorption.
Q43. Which of the following substances is normally not found in the urine of a healthy person?
A. Urea
B. Sodium
C. Protein
D. Water
C. ProteinNormally, urine contains no detectable protein (albumin). The glomerulus prevents large molecules like proteins and blood cells from passing into the filtrate. Presence of protein in urine (proteinuria) indicates kidney damage, such as in glomerulonephritis or diabetic nephropathy. Temporary proteinuria can occur after heavy exercise.
Q44. The average number of heartbeats per minute in a newborn baby is approximately:
A. 40-60
B. 70-80
C. 100-160
D. 200-220
C. 100-160Newborn babies have a much faster heart rate than adults, typically 100 to 160 beats per minute. This is because they have a smaller heart and a higher metabolic rate relative to body size. The heart rate gradually decreases during childhood, reaching adult rates (60-100 bpm) by adolescence. Fever and crying can increase a baby’s heart rate further.
Q45. The process of expelling urine from the urinary bladder is called:
A. Excretion
B. Micturition
C. Filtration
D. Secretion
B. MicturitionMicturition, also called urination, is the process of releasing urine from the urinary bladder. When the bladder contains about 300-400 mL of urine, stretch receptors send signals to the spinal cord and brain, creating the urge to urinate. The brain can voluntarily delay urination by keeping the external urethral sphincter closed.
Q46. The main function of the collecting duct in the nephron is to:
A. Filter blood
B. Reabsorb glucose
C. Carry urine from multiple nephrons to the renal pelvis and concentrate urine
D. Secrete urea into the filtrate
C. Carry urine from multiple nephrons to the renal pelvis and concentrate urineThe collecting duct receives filtrate from several nephrons. As it passes through the medulla of the kidney, water is reabsorbed (under the influence of ADH hormone), concentrating the urine. The final concentrated urine then drains into the renal pelvis and then into the ureter. Without the collecting duct, humans could not produce concentrated urine.
Q47. The hormone that controls how much water is reabsorbed by the kidneys (making urine concentrated or dilute) is:
A. Insulin
B. Adrenaline
C. Antidiuretic hormone (ADH)
D. Thyroxine
C. Antidiuretic hormone (ADH)ADH (also called vasopressin) is produced in the hypothalamus and released from the pituitary gland. When the body is dehydrated, ADH increases water reabsorption in the collecting ducts, producing concentrated urine. When excess water is drunk, ADH decreases, producing dilute urine. Alcohol inhibits ADH, causing increased urine output and dehydration.
Q48. In the human excretory system, the renal artery carries:
A. Oxygenated blood containing waste products to the kidney
B. Deoxygenated blood away from the kidney
C. Filtered blood from the kidney to the heart
D. Urine to the bladder
A. Oxygenated blood containing waste products to the kidneyThe renal artery branches directly from the aorta and carries oxygenated blood (along with dissolved waste products like urea) to the kidney for filtration. After the kidney filters the blood and removes wastes, the cleaned blood leaves through the renal vein (which carries deoxygenated blood back to the inferior vena cava and heart).
Q49. The reason why birds and reptiles excrete uric acid instead of urea is:
A. Uric acid is more toxic but requires more water
B. Uric acid is less toxic and requires very little water, which is good for dry environments and egg development
C. They cannot produce urea
D. Uric acid is produced in their muscles
B. Uric acid is less toxic and requires very little water, which is good for dry environments and egg developmentUric acid is a white, paste-like waste that is almost insoluble in water. Excreting it saves water, which is important for birds and reptiles living in dry habitats. Additionally, developing embryos inside eggs cannot eliminate liquid waste; uric acid crystallizes harmlessly and remains in the eggshell. This adaptation is crucial for reproduction on land.
Q50. If both kidneys fail completely and dialysis is not available, what is the most likely outcome?
A. The person can survive with the liver taking over kidney function
B. The person will develop high blood pressure but survive
C. The person will accumulate toxins (uremia) and eventually die within days to weeks
D. The person will excrete all wastes through the skin
C. The person will accumulate toxins (uremia) and eventually die within days to weeksComplete kidney failure is fatal without medical intervention. Without dialysis or a kidney transplant, urea, creatinine, and other toxins build up in the blood (uremia), causing nausea, seizures, coma, and death. Electrolyte imbalances and fluid overload also occur. No other organ can fully replace the filtering function of the kidneys. Death typically occurs within 1-2 weeks.
